Program

Program for ACAN 2012

Week 1: Neural Integration & Excitability                             

Lectures include:
• Basic circuit analysis
• Principles of electrophysiological recording
• Biophysics and molecular biology of ion channels
• Data analysis
Labs include:
• Patch clamping cortical brain slices
• Whole-cell current and voltage clamp
• Single-channel recording and cell-free patches
• Neuromodulation of action potentials
(During week 1, each pair of students will have a dedicated instructor to ensure rapid mastery of patch clamping.)

Week 2: Synaptic transmission

Lectures include:
• Fundamentals of synaptic transmission
• Short- and long-term synaptic plasticity
• Learning and memory
• Neuronal networks
(General interest lectures on neuroscience topics will also be given.)
Labs include:
• Pharmacology of synaptic transmission
• Long-term potentiation (LTP)
• Dendritic recordings
• Patching pairs of neurons
(During weeks 2 and 3, lab instructors will circulate more freely, encouraging cross-fertilisation of approaches and ideas.)

Week 3: Fluorescence Imaging

Lectures include:
• Introduction to fluorescence microscopy
• Principles of calcium imaging
• Manipulating neurons with light
(General interest lectures on neuroscience topics will also be given.)
Labs include:
• Simultaneous electrophysiology and Ca imaging of single neurons
• Confocal microscopy
(During weeks 2 and 3, lab instructors will circulate more freely, encouraging cross-fertilisation of approaches and ideas.)

Laboratory Project

• Each pair of students will have two full days in which to carry out a small research project of their own choosing.
• Throughout the course, students are encouraged to ‘brainstorm’ with faculty about possible projects.
• Your project might be a pilot experiment for research you wish to conduct in your own lab. In this case, you may like to bring along compounds to test.

Download the full ACAN 2012 program (Last updated 27 Oct 2011)